Yeah, I think I’ll go with proxmox as a first attempt — it seems to fit what I’m looking for and the feedback here has been pretty positive on that front. My main concern now is figuring out how to provision the hdds so that a jellyfin lxc can utilize it, nextcloud could use it, and I can save (configuration) backups to it. I’m comfortable with zfs in general (run that on my desktop), but I was under the impression that raid10 would be more performant with the same redundancy, when using 4 disks in raid10. Any one disk could fail, writes are at the speed of the disk because of mirror, and reads are 2x. I lose usable disk space, but I think 16tb is enough for me (for now of course haha). Am I wrong though on the zfs vs raid10? I guess actually I could use zfs, create a single pool with two mirrored vdevs. I am not sure how that would affect future growth, but should do really well for now. Does that sound like a reasonable thing to do, in your opinion?
Pharmaceutical companies are actually legally required to find out if you’re misusing their product or taking it in an undirected way, and report that to the FDA. Well, has been that way historically, anyhow. If you even work for a pharmaceutical company and you overhear at a weekend barbecue that someone has not taken a dose or doubled a dose etc, you’re obligated to report it within 24 hours.