In our latest attempts to make lab rats immortal, a new compound has been shown to reverse late stage Alzheimer’s disease in lab mice. This is a rare case where the title isn’t even clickbait.

  • gibmiser@lemmy.world
    link
    fedilink
    English
    arrow-up
    49
    arrow-down
    2
    ·
    12 days ago

    In a mouse model. The mice don’t have alzheimers they have… something we gave them that looks like it… Hopefully it is similar enough

    • Dr. Bob@lemmy.ca
      link
      fedilink
      English
      arrow-up
      18
      arrow-down
      8
      ·
      12 days ago

      We did something to the mice then rescued it in a different way. Hooray! Next we’ll save test tubes from cancer…again.

      • scarabic@lemmy.world
        link
        fedilink
        English
        arrow-up
        15
        ·
        12 days ago

        If you can’t get excited by incremental advancements, you should probably unsubscribe from science as a topic.

        • Dr. Bob@lemmy.ca
          link
          fedilink
          English
          arrow-up
          4
          ·
          12 days ago

          Dude it’s worse than that. I was a working neuroscientist for almost twenty years. So…jaded.

            • Dr. Bob@lemmy.ca
              link
              fedilink
              English
              arrow-up
              2
              ·
              11 days ago

              There is a lot of incremental research that gets transformed into ZOMG YOU GUYS!!! by the research office. The journals are full of papers demonstrating a complete rescue of a disease model ( and I’m an author on some of them). What the papers are really demonstrating is the inadequacy of the animal model.

    • piconaut@lemmy.ca
      link
      fedilink
      English
      arrow-up
      5
      ·
      12 days ago

      Yeah, I didn’t read the whole thing but apparently only in 5xFAD mice. I wish they would have also tried it in a Tau model like PS19.

    • SaveTheTuaHawk@lemmy.ca
      link
      fedilink
      English
      arrow-up
      4
      arrow-down
      2
      ·
      12 days ago

      There has been a fucking epidemic of MD/scientists running to the media with miracle cures lately.

      Mice to not get Alzheimers, they were engineered to show one aspect of the disease that has been promoted by fraudulent studies. As for the reversal, mouse brains are highly plastic and similar to a human baby, nothing like a >60 year old.