The article doesn’t read as very concerning. Too much of anything usually means bad. Under the right conditions anything can be bad. Figuring out what can be bad and when it can be bad can often take decades. Don’t stress too much on trying to optomize out anything that can do you harm in a diet. You’d have nothing left to eat and even the greatest collective of biologist getting together to make the greatest nutritional shake meal replacement would probably miss something that causes issues decades down the line or people drink too much and overdose